KQ8 Association between fat loss potassium intake and you can cardiovascular disease, cardiovascular system problem, heart attack, kidney disease, and you may death
Lookup Approach: “Potassium, Dietary”[Mesh] Otherwise potassium[tiab] Or KLOR-CON[tiab] Otherwise KCL[tiab] And you will “Cardio Ailment”[Mesh] Otherwise heart disease*[tiab] Otherwise acute coronary syndrome* [tiab] Otherwise “volatile angina” Otherwise myocardial infarct* Or coronary attack Or strokes Or “cardio incapacity” Otherwise “coronary heart state” Otherwise kidney function* Or kidney situation*[tiab] Or “creatinine clearance” Otherwise “serum creatinine” Otherwise albuminuria Otherwise proteinuria Otherwise “glomerular filter” Or “prevent phase kidney state”[tiab] Or “Renal Ailment”[Mesh] Or chronic renal situation*[tiab] Otherwise “albumin-to-creatinine proportion” Otherwise “albumin to creatinine proportion” Or renal brick* Otherwise serious kidney injur* Or “renal calculi” Otherwise renal lithiasis Or nephrolith* Otherwise nephrolithiasis Or kidney brick Otherwise kidney calculi Or “Mortality”[Mesh] Or mortality[sh] Or mortality[tiab] And you can “Possible Education”[Mesh]) Or “Case-Control Training”[Mesh:NoExp] Otherwise “prospective cohort” Otherwise “nested situation-control” Otherwise “metabolic research” Otherwise check out*[tiab] Or clinical trial* And you can human beings[MESH] Or ((inprocess[sb] Or journalist[sb] Or pubmednotmedline [sb]) Maybe not (mice[ti] Otherwise mouse[ti] Or rats[ti] Otherwise animals[ti]))
Along with site exploration Aburto ainsi que al., 2013 thirty six ; Dickinson mais aussi al., 2006 38 ; NHLBI, 2013 5 ; Beyer ainsi que al., 2006 39 ; DRI statement; and other health-related feedback understood from the scoping research.
The newest important endpoint selected to have devotion of the Tolerable Higher Consumption Peak (UL) is actually blood circulation pressure. 2 Brand new IOM figured the connection ranging from sodium consumption and you can blood pressure level is continued without a noticeable threshold for example it try difficult to truthfully put a good UL, specifically just like the other factors (pounds, get it done, potassium consumption, weight reduction trend, alcoholic beverages consumption, and you can hereditary items) as well as apply to blood pressure levels. The newest IOM lay new UL to have salt at the dos,300 mg each day for all those old 14 many years as well as over, which have straight down viewpoints of these step 1-13 years of age. For the dose-effect trials, it top was are not the next stage over the AI that are checked. The newest ULs for children have been extrapolated throughout the adult UL situated into average time intakes. It ought to be noted that the UL is not a recommended consumption and you will, as with almost every other ULs, there is no advantage to ingesting membership above the AI. step one
II. The key Issues
Because of the multitude of current input studies of sodium reduction and you can potassium as well as the suitability and you may robustness of one’s RCT design to assess the effect out of interventions, we will limitation KQ step one, step 3, 5, and you may 7 to help you RCTs. Good investigations procedures might be chosen as well as type in from the Tech Professional Panel (TEP) and you will articles expert supporting that it clinical opinion.
Elizabeth. Investigation Synthesis
Prospective Fellow Reviewers must reveal people financial issues of great interest greater than simply $10,one hundred thousand and every other relevant providers otherwise top-notch disputes of interest. Desired Peer Reviewers might not have people financial disagreement of great interest more than $ten,100. Fellow writers whom reveal potential business otherwise professional problems interesting can get submit comments with the draft records from public opinion system.]]
Plus source mining Aburto mais aussi al., 2013 24 ; Adler et al. www.datingranking.net/nl/curves-connect-overzicht/, 2014 31 ; Johnson ainsi que al., 2015 twenty-five ; McMahon ainsi que al., 2015 29 , Poggio ainsi que al., 2015 thirty two ; Graudal ainsi que al., 2014 33 ; Suckling ainsi que al., 2010 34 ; Stazzullo mais aussi al., 2009 thirty-five ; DRI declaration; and other systematic product reviews understood throughout the scoping lookup
Together with site mining Aburto et al., 2013 36 ; Dickinson ainsi que al., 2006 38 ; NHLBI, 2013 5 ; DRI report; and other scientific feedback identified about scoping research
- In incorporated studies perhaps not reporting on the prespecified outcomes: you to definitely study-particular hypertension level
- Kidney brick occurrence
- The guy FJ, Li J, Macgregor GA. Effect of expanded-identity more compact salt cures toward blood circulation pressure. Cochrane Databases Syst Rev. 2013;4(1469-493X (Electronic)):Cd004937. doi: 1858.CD004937.pub2. PMID: 23633321.
- McMahon EJ, Campbell KL, Bauer JD, ainsi que al. Altered dietary sodium consumption for those who have persistent renal disease. Cochrane Database Syst Rev. 2015(2):CD010070. doi: 1858.CD010070.pub2. PMID: 25691262.
